Chromosome assignments of genes for human Na (+) -dependent phosphate co-transporters NaPi-3 and NPT-1

Miyamoto, K.; Tatsumi, S.; Yamamoto, H.; Katai, K.; Taketani, Y.; Morita, K.; Takeda, E.

Tokushima Journal of Experimental Medicine 42(1-2): 5-9

1995


ISSN/ISBN: 0040-8875
PMID: 7570593
Document Number: 440537
Chromosome assignments for the genes encoding human renal high affinity Na/phosphate co-transporters NaPi-3 and NPT-1 were derived by analyzing somatic cell hybrid DNAs. Polymerase chain reaction (PCR), using primers specific for two human Na/Pi co-transporters demonstrated that the genes for NaPi-3 was assigned to human chromosome 5 while that for NPT-1 was assigned to human chromosome 6. Renal phosphate transporter genes may be candidates for causing hereditary hypophosphatemia with hypercalciuria in humans.

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