Successful long-term pancreatic islet cell xenotransplantation and functional tolerance in NOD mice
Ljung, T.; Pittman, K.; Thomas, F.T.
Transplantation Proceedings 27(1): 1351-1352
1995
ISSN/ISBN: 0041-1345 PMID: 7878908 Document Number: 439839
These findings raise a high degree of optimism concerning the potential application of this modality in higher animals. Studies are currently in process in our laboratory to apply this immunosuppressive regimen to higher animals using xenogeneic pig islets in a preclinical model that would provide the basis for future clinical trials.
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