Biochemical mechanisms of protective action of enomelanin during hemic hypoxia caused by carbon monoxide
Barinova, I.E.; Galkin, B.N.; Golovenko, N.I.; Osetrov, V.E.; Savva, V.M.
Ukrainskii Biokhimicheskii Zhurnal 67(5): 89-93
1995
ISSN/ISBN: 0201-8470 PMID: 8830443 Document Number: 439325
Prophylactic injection of enomelanine has been studied for its effect on hemic hypoxia and on different parts of breathing system. The enomelanine was shown to be effective for decreasing the level of carboxyhemoglobin and for protection from succinate dehydrogenase and cytochromoxidase. The authors think that these effects of enomelanine are conditioned not only by its anti-hypoxia abilities, but also by the capacity to activate the alternative protective mechanisms of the cell.