Anaphylactic shock by ophthalmic wash solution containing chlorhexidine
Okuda, T.; Funasaka, M.; Arimitsu, M.; Umeda, T.; Wakita, K.; Koga, Y.
Masui. Japanese Journal of Anesthesiology 43(9): 1352-1355
1994
ISSN/ISBN: 0021-4892 PMID: 7967032 Document Number: 438634
A 58 year-old male patient developed anaphylactic shock, possibly due to the use of chlorhexidine as ophthalmic wash solution. He was successfully resuscitated without any sequelae. The patient had increased levels of both histamine and tryptase. The skin test for allergy resulted in strong positive to chlorhexidine. There have been many reports regarding severe adverse reactions associated with use of chlorhexidine. It is necessary to pay attention to anaphylactic shock due to chlorhexidine.