Significance of para-aortic lymph node dissection in patients with advanced and recurrent gastric cancer
Inada, T.; Ogata, Y.; Andoh, J.; Ozawa, I.; Matsui, J.; Hishinuma, S.; Shimizu, H.; Kotake, K.; Koyama, Y.
Anticancer Research 14(2b): 677-682
1994
ISSN/ISBN: 0250-7005 PMID: 8010726 Document Number: 437854
Among 243 patients who underwent radical gastrectomy for advanced gastric cancer, 19 patients underwent radical gastrectomy with extended lymphadenectomy including cancer-positive para-aortic lymph nodes. Their prognosis was unexpectedly good, with a mean postoperative survival time of 24.1 months and a 2-year-survival rate of 42.4 percent. Another 4 patients developed para-aortic lymph node recurrence detected by computed tomographic scan during a follow-up examination. These 4 patients were treated with macroscopic curative dissection of the para-aortic lymph nodes. Although 2 of the 4 patients died within 6 months after re-operation, the prognosis of the other two patients was rather good when treated with active combination chemotherapy consisting of 5-fluorotiracil, adriamycin and cisplatin. Dissection of para-aortic lymph nodes is considered of valuable in the treatment of advanced gastric cancer, and dissection of the para-aortic lymph node recurrence may also be valid when combined with potent chemotherapy.