Ovarian lymphoma and serous carcinoma of low malignant potential arising in the same ovary. A case report with literature review of 14 primary ovarian lymphomas

Skodras, G.; Fields, V.; Kragel, P.J.

Archives of Pathology and Laboratory Medicine 118(6): 647-650

1994


ISSN/ISBN: 0003-9985
PMID: 8204013
Document Number: 437518
Ovarian lymphoma was incidentally identified in the ovary of a 31-year-old patient who underwent surgical exploration for an ovarian mass. The 6-cm mass was a serous carcinoma of low malignant potential and was located in the same ovary with the lymphoma. The lymphomatous nodule measured 1.5 cm and was diagnosed as diffuse, large-cell lymphoma of B-cell phenotype. Careful search during surgery, as well as extensive postoperative workup, showed no evidence of spread of either tumor type beyond the ovary. In a small pilot study, we examined 37 randomly selected oophorectomy specimens to determine the possible occurrence of lymphoid tissue in the ovary that could serve as substrate for development of ovarian lymphoma. Variable numbers of lymphocytes were identified in 34 of 37 ovaries, mainly in association with common ovarian lesions. This finding and the clinicopathologic data of 14 other reported cases of ovarian lymphoma provide evidence that lymphomas can arise primarily in the ovary.

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