Community treatment with ivermectin for onchocerciasis in the east Usambara mountains
Mwetta, E.; Hills, E.
East African Medical Journal 71(12): 790-791
1994
ISSN/ISBN: 0012-835X PMID: 7705249 Document Number: 437517
Ivermectin 150mcg/kg was given orally to 743 patients with positive skin snips for Onchocerca volvulus and to 697 residents in two villages in the Usambara mountains. 620 villagers attended for a second dose. On direct questioning, 98.7% patients with +ve skin snips and 91.8% villagers given mass chemotherapy admitted to adverse reactions. After a second dose, 16.6% had mild reactions. No serious problems were encountered. 167 of 170 repeat skin snips were negative. Repeated administration of ivermectin is well tolerated and offers a chance of reducing the burden of onchocerciasis in the Usambara mountains.
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