Protein kinase C-like immunoreactivity in gerbil hippocampus after a transient cerebral ischemia
Gajkowska, B.; Domańska-Janik, K.; Viron, A.
Folia Histochemica et Cytobiologica 32(2): 71-77
1994
ISSN/ISBN: 0239-8508 PMID: 7958073 Document Number: 436958
This study describes immunocytochemical distribution of the protein kinase C (PKC) subspecies: alpha, beta and gamma in the CAI sector of gerbil hippocampus. Immunolabelling was performed with 10 nm gold-antibody complexes against each of the PKC subspecies. The subspecies of PKC were expressed specifically in different populations of hippocampal cells. An enhanced PKC immunoreactivity was noted in the animals after ischemia. We propose that this phenomenon reflects an activation of PKC in the early phase of brain ischemia.