Guillain-Barré syndrome after bone marrow transplantation
Perry, A.; Mehta, J.; Iveson, T.; Treleaven, J.; Powles, R.
Bone Marrow Transplantation 14(1): 165-167
1994
ISSN/ISBN: 0268-3369 PMID: 7951108 Document Number: 435937
A patient with chronic myeloid leukemia developed Guillain-Barre syndrome 4 months after allogeneic bone marrow transplantation. Clinical improvement occurred after a series of plasma exchanges. A relapse of the Guillain-Barre syndrome was also successfully treated with plasma exchange, with an eventual near complete recovery. Reactivation of cytomegalovirus infection as manifested by antigenemia 2 months prior to the weakness was probably the precipitating event in this patient. We advocate early treatment of posttransplant Guillain-Barre syndrome with plasma exchange.