The chemistry of proteolysis
Rumsh, L.D.
Bioorganicheskaia Khimiia 20(2): 85-99
1994
ISSN/ISBN: 0132-3423 PMID: 8155082 Document Number: 435927
Experimental data obtained in this laboratory led to the determination of the mechanism of hydrolysis of peptide bonds by proteolytic enzymes. Efficiency and specificity of proteinases are explained in terms of the substrate state in the productive enzyme-substrate complex. An advanced classification of proteinases based on their mechanism of action is suggested.
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