Budd-Chiari syndrome associated with antiphospholipid antibodies in a child: report of a case and review of the literature
Saca, L.F.; Szer, I.S.; Henar, E.; Nanjundiah, P.; Haddad, Z.H.; Quismorio, F.P.
Journal of Rheumatology 21(3): 545-548
1994
ISSN/ISBN: 0315-162X PMID: 8006900 Document Number: 435407
Budd-Chiari syndrome, hypertension, and thrombocytopenia developed in a 6-year-old girl as manifestations of primary antiphospholipid antibody syndrome (APS). She improved with systemic corticosteroid and anticoagulation therapy. Anticardiolipin antibodies were found in the patient, her mother and 3 siblings, suggesting the importance of genetic factors. The clinical features of an APS in children is reviewed.