Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of rifampicin on theophylline pharmacokinetics in human beings

Rao, S.; Singh, S.K.; Narang, R.K.; Rajagopalan, P.T.

Journal of the Association of Physicians of India 42(11): 881-882

1994

ISSN/ISBN: 0004-5772
PMID: 7868490
Document Number: 434024
Theophylline pharmacokinetics before and after rifampicin administration was studied in 10 healthy volunteers. It was seen that Rifampicin significantly increased the volume of distribution of theophylline by 23.41% (p < 0.01) and its metabolic clearance by 47.65% (P < 0.05). This has got clinical significance in the treatment of patients of pulmonary tuberculosis with chronic obstructive airways disease where both the drugs may have to be given concurrently.

Document emailed within 1 workday
Secure & encrypted payments

Reitberg, D.P.; Klarnet, J.P.; Carlson, J.K.; Schentag, J.J. 1983: Effect of metronidazole on theophylline pharmacokinetics Clinical Pharmacy 2(5): 441-444
Ramachandran, G.; Hemanth Kumar, A.K.; Srinivasan, R.; Geetharani, A.; Sugirda, P.; Nandhakumar, B.; Nandini, R.; Tharani, C.B. 2012: Effect of rifampicin and isoniazid on the steady state pharmacokinetics of moxifloxacin Indian Journal of Medical Research 136(6): 979-984
Wemhöner, S.; Oellerich, M.; Sybrecht, G. 1981: Theophylline therapy in obstructive respiratory diseases. 1. Bioavailability and pharmacokinetics of various theophylline preparations Praxis und Klinik der Pneumologie 35(1): 36-41
Dayer, P.; Deom, A.; Roth, M. 1982: Absorption of theophylline: pharmacokinetics of 2 water-alcohol solutions of theophylline Pharmaceutica Acta Helvetiae 57(1): 27-32
Rybolovlev, I.R. 1984: Prediction of the effect of xenobiotics on human beings Farmakologiia i Toksikologiia 47(1): 110-114
Hirsh, D.C.; Wiger, N. 1977: Effect of tetracycline upon transfer of an R plasmid from calves to human beings American Journal of Veterinary Research 38(8): 1137-1139
Acocella, G.; Segre, G. 1974: Kinetics of rifampicin and desacetyl-rifampicin in plasma, bile, and urine in humans and the effect of repeated administrations Acta Pharmaceutica Suecica 11(6): 657-658
Jiang, C.S.; Kilfeather, S.A.; Pearson, R.M.; Turner, P. 1984: The stimulatory effects of caffeine, theophylline, lysine-theophylline and 3-isobutyl-1-methylxanthine on human sperm motility British Journal of Clinical Pharmacology 18(2): 258-262
Shorin, V.A.; Kunrat, L.A. 1974: Rifampicin pharmacokinetics in rabbits Antibiotiki 19(11): 978-981
Ginzburg, T.S.; Drabkina, R.O. 1972: Antitubercular activity and pharmacokinetics of rifampicin Antibiotiki 17(7): 607-611
Oellerich, M.; Sybrecht, G.W. 1984: Pharmacokinetics of theophylline British Journal of Clinical Practice. Supplement 35: 3-4
Jaruratanasirikul, S. 1998: The pharmacokinetics of oral rifampicin in AIDS patients Journal of the Medical Association of Thailand 81(1): 25-28
Schaumann, R.F.; Shah, P.M. 1992: Effect of amphotericin B alone or in combination with rifampicin on phagocytosis of Candida species by human polymorphonuclear leukocytes Methods and Findings in Experimental and Clinical Pharmacology 14(10): 753-758
Lapalus, P.; Blaive, B.; Bugnas, B. 1981: Clinical pharmacokinetics of a microcrystalline theophylline Therapie 36(1): 35-40
Caplain, H.; Thebault, J.J.; Necciari, J. 1999: Clopidogrel does not affect the pharmacokinetics of theophylline Seminars in Thrombosis and Hemostasis 25(Suppl 2): 65-68
Schwartz, J.I.; Bachmann, K.A.; Bond, L.W.; Mahajan, V.K. 1982: Impact of cimetidine on the pharmacokinetics of theophylline Clinical Pharmacy 1(6): 534-538
Schmidt, G.; Ranke, C.; Creutzig, H.; Oellerich, M.; Sybrecht, G.W. 1983: Optimizing of therapy with theophylline preparations in obstructive respiratory diseases. 4. Effect of theophylline on mucociliary clearance and maximal inspiratory mouth occlusion pressure Praxis und Klinik der Pneumologie 37(4): 154-160
Brandstetter, Y.; Kaplanski, J.; van Creveld, C.; Ben-Zvi, Z. 1986: Theophylline pharmacokinetics in pregnant and lactating rats Research Communications in Chemical Pathology and Pharmacology 53(2): 269-272
Cazzola, M.; Lobefalo, G.; Lupis, F.; Vanacore, L.; Martucci, P.; D'Amato, G. 1989: The effects of cefonicid on the pharmacokinetics of a once-a-day theophylline formulation International Journal of Clinical Pharmacology Research 9(3): 169-173
Koup, J.R.; Vawter, T.K. 1983: Theophylline pharmacokinetics in an extremely obese patient Clinical Pharmacy 2(2): 181-183