The results of catheterization and the x-ray angiographic assessment of cardiac contractility and volume in primary pulmonary hypertension
Samko, A.N.; Savchenko, A.P.; Chazova, I.E.; Lazutkina, V.K.; Mareev, V.Iu.; Belenkov, I.N.
Terapevticheskii Arkhiv 66(5): 62-66
1994
ISSN/ISBN: 0040-3660 PMID: 7940343 Document Number: 433731
To ascertain the role of invasive investigations in the diagnosis of primary pulmonary hypertension (PPH), 12 PPH patients underwent catheterization of the left and right heart compartments, contrast right and left ventriculography and oximetry. Compared to control values, the patients had high pressure in the pulmonary artery and right ventricle. Some of them exhibited elevated pressure in the right atrium. Pulmonary artery wedge pressure, left ventricular end-diastolic and systolic, diastolic pressure in the aorta did not differ significantly from those in the controls. Right and left ventriculography revealed an increase in the end-systolic and end-diastolic volumes of the right ventricle which diminished its stroke index and ejection fraction. The latter two were reduced in the left ventricle also. Because the procedure was well tolerated by the patients, it is recommended for PPH diagnosis and follow-up.