The epidermal growth factor induces specific changes in the expression of small RNA and of the set of small RNP in A-431 cells

Konstantinova, I.M.; Kulichkova, V.A.; Turoverova, L.V.; Petukhova, O.A.; Kozhukharova, I.V.; Teslenko, L.A.

Tsitologiia 36(2): 174-181

1994


ISSN/ISBN: 0041-3771
PMID: 7809966
Document Number: 433599
Specific small ribonucleoprotein (alpha-RNP) complexes have been identified and characterized in the human epidermal carcinoma A-431 cells. The alpha-RNP complexes contain Alu-homologous small RNA, along with other small antisense RNA species. The epidermal growth factor (EGF) has been shown to induce selective specific changes in the expression of the small alpha-RNAs, the expression of the Alu-like RNA being repressed. Specific changes in the protein composition of the alpha-RNP complexes have been detected under the influence of EGF.

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