Human chorionic gonadotrophin therapy in male infertility
Amelar, R.D.; Dubin, L.
JAMA 237(22): 2423
1977
ISSN/ISBN: 0098-7484 PMID: 12335036 Document Number: 433408
A response to a doctor's question regarding the therapeutic use of human chorionic gonadotropin (HCG) in a 24-year-old male with primary infertility is presented. The subject had only scattered spermatogenesis, but low-normal follicle stimulating hormone (FSH) and testosterone (T) levels. In reply, the therapeutic injection of 4000 units HCG twice a week for 10 weeks is reported. Generally, improvement in semen quality should begin about 3 months after completion of the injection series. Frequently, treatment will be accompanied by an increase in libido and improved sexual performance. Transient nipple tenderness and gynecomastia was noted in less than 5% of the patients toward the end of treatment.