Lyme disease: a review with emphasis on the pregnant woman
Smith, L.G.; Pearlman, M.; Smith, L.G.; Faro, S.
Obstetrical and Gynecological Survey 46(3): 125-130
1991
ISSN/ISBN: 0029-7828 PMID: 2014072 Document Number: 4319
As the prevalence of Lyme disease increases in the general population around the world, more pregnant women will be infected. In order for the pregnant patient to receive prompt treatment, early symptoms of this disease should be recognized. Although the precise mechanism of fetal loss is unknown, several studies suggest the fetus may be at risk for teratogenesis in early pregnancy, and preterm delivery or loss during late infection, although neither is proven. Documented adverse fetal-neonatal outcome is limited. Beyond the first several weeks of infection, serological determinations are the most practical laboratory aid in diagnosis. Appropriate antibiotic therapy is highly efficacious for the mother but the effect of early treatment of the fetus is unknown. Recommendations regarding fetal evaluation in women infected with the Lyme spirochete awaits further clinical experience.
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