Interleukin-6: friend or enemy? Latest findings on the clinical aspects of IL-6
Fogarasi, M.; Kubala, E.; Bíró, J.; Falus, A.; Nemesánszky, E.
Orvosi Hetilap 135(38): 2075-2082
1994
ISSN/ISBN: 0030-6002 PMID: 7936613 Document Number: 431267
The authors summarize the recent findings obtained in the field of inflammatory cytokines with particular attention on interleukin-6 (IL-6). After a short review of the molecular biology and of the cellular effects of IL-6, the most important clinical relations of IL-6 in hepatic diseases, in non-specific inflammatory bowel diseases (Crohn's disease and ulcerative colitis) and in certain autoimmune diseases are provided. The simultaneous discussion of molecular and clinical data contribute to the understanding of pathomechanisms.