Ceftazidime as monotherapy for fever and neutropenia: experience in a community hospital
Bizette, G.A.; Brooks, B.J.; Alvarez, S.
Journal of the Louisiana State Medical Society Official Organ of the Louisiana State Medical Society 146(10): 448-452
1994
ISSN/ISBN: 0024-6921 PMID: 7798779 Document Number: 430921
Fever and neutropenia is occurring in a wider variety of clinical settings, and the proper antibiotic therapy for its treatment is an area of debate. Our study is a retrospective analysis of the experience of the Oncology Division of the Medical Center of Baton Rouge, which used ceftazidime as monotherapy in the empiric treatment of fever and neutropenia. A total of 53 episodes in 38 patients were studied. Using ceftazidime as monotherapy in our study population was associated with an 8% mortality rate, indicating that monotherapy is a viable option for the treatment of fever and neutropenia.