The influence of hypothalamically administered reserpine on the sexual behavior of the female cat
Cerny, V.A.
Psychopharmacology 50(3): 269-274
1976
ISSN/ISBN: 0033-3158 PMID: 826972 DOI: 10.1007/bf00426843Document Number: 430728
Ovariectomized cats with intracerebral implants of reserpine, a monoamine depletor, were tested for sexual behavior by introducing them to sexually vigorous males and by artificial stimulation. Approximately 1/3 of the animals mated in response to reserpine and another 1/3 exhibited some components of sexual behavior. The behavior exhibited by these animals had none of the frenzy of normal estrous behavior. Some components of the normal pattern were missing while all others were curtailed in duration and vigor. These animals responded with normal sexual behavior to intracerebrally and systemically administered estrogen. The unusual sexual behavior in response to reserpine might be due to the release of these behavioral patterns from a monoamine system, inhibitory to sexual behavior.
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