Hypoglycemic effects of leucodelphinidin derivative isolated from Ficus bengalensis (Linn)
Geetha, B.S.; Mathew, B.C.; Augusti, K.T.
Indian Journal of Physiology and Pharmacology 38(3): 220-222
1994
ISSN/ISBN: 0019-5499 PMID: 7814088 Document Number: 430607
A Leucodelphinidin derivative isolated from the bark of Ficus bengalensis Linn demonstrated hypoglycemic action at a dosage of 250 mg/kg given both in normal and alloxan diabetic rats. It's action is closely similar to that of an effective dose of glibenclamide (2 mg/kg) tested under the same conditions. However, after a glucose load the plant product is only just significantly active but not as effective as the sulfonylurea. This efficacy of the plant product as a hydroglycemic agent adds to its other therapeutic effects, as it belongs to the class of flavonoids.