Growth factors and electromagnetic fields in bone
Fitzsimmons, R.J.; Baylink, D.J.
Clinics in Plastic Surgery 21(3): 401-406
1994
ISSN/ISBN: 0094-1298 PMID: 7924137 Document Number: 430415
Stimulation of bone by low-energy electromagnetic fields (EMFs) may prove to be an efficient therapy for skeletal disorders. The study discussed in this article demonstrates that an EMF of 15.3 Hz can increase the proliferation rate of an osteosarcoma cell line, TE-85. The increase in cell proliferation was associated with an increase in binding sites for insulin-like growth factor II and an increase in mitogen activity in culture media.