A case of nemaline myopathy combined with recurrent rhabdomyolysis
Ishikawa, A.; Tanaka, S.; Ogawa, Y.; Fukushima, N.; Takase, A.; Wagatsuma, Y.; Goto, Y.; Sugie, H.; Kajii, N.
No to Hattatsu 26(4): 340-344
1994
ISSN/ISBN: 0029-0831 PMID: 8074897 Document Number: 430193
A four-year-old boy with cerebral palsy showed marked myoglobinemia and developed acute renal failure. Peritoneal dialysis and exchange transfusion resulted in saving the patient. He had a second episode of rhabdomyolysis after one month. Renal failure did not develop due to forced solute-alkaline diuresis therapy. Muscle biopsy revealed nemaline bodies by the Gomori trichrome stain. Serum and muscle carnitine showed a marked decrease.