Embryo reduction in multiple pregnancies. a French multicenter study
Dommergues, M.; Aknin, J.; Boulot, P.; Nisand, I.; Lewin, F.; Oury, J.F.; Herlicoviez, M.; Dumez, Y.; Evans, M.I.
Journal de Gynecologie Obstetrique et Biologie de la Reproduction 23(4): 415-418
1994
ISSN/ISBN: 0368-2315 PMID: 8051370 Document Number: 430134
To study the outcome of multifetal pregnancy embryo reductions (MFPR) in France. A retrospective questionnaire multicenter survey was conducted in 11 French centers. 262 consecutive MFPR were collected. Miscarriage and prematurity rates were analyzed as a function of the starting number of embryos, the finishing number after MFPR, and the technique of MFPR. There were 41 pregnancy losses before 24 weeks (16%), and 221 deliveries at 25 menstrual weeks or later (84%). Prematurity was significantly correlated to the finishing number of embryos following MFPR. However, even when a single embryo was left, there were 30% of premature deliveries. MFPR decreases the risk of prematurity in multifetal pregnancies of high order, and this is best achieved when a single embryo is left.