Pseudomonas microcins: characterization and effect of iron concentration

Barberis, I.L.; Pájaro, M.C.; Albesa, I.

Revista Latinoamericana de Microbiologia 36(2): 101-106

1994


ISSN/ISBN: 0187-4640
PMID: 7973176
Document Number: 429986
Antibacterial substances were found in Pseudomonas, they were heat and trypsin resistant, molecular weight less than 10,000 daltons, produced in minimal media, optimum pH 7.0. Methionine and glycine inhibited them; other amino acids produced less antagonistic effect. An inverted relationship between susceptibility to microcin and Fe3+ concentration was observed in experiments with iron-depleted strains. Pseudomonas was sensitive to its own microcin in iron-free medium; this is an important finding in the study of the immunity of microcin-producing strains.

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