Arteritis of both carotid arteries in a patient with focal, crescentic glomerulonephritis and anti-neutrophil cytoplasmic autoantibodies
Logar, D.; Rozman, B.; Vizjak, A.; Ferluga, D.; Mulder, A.H.; Kallenberg, C.G.
British Journal of Rheumatology 33(2): 167-169
1994
ISSN/ISBN: 0263-7103 PMID: 8162485 Document Number: 429678
We report a 32-yr-old woman who suffered a stroke as a consequence of arteritis of both internal carotid arteries confirmed by selective carotid arteriography. Laryngeal inflammation and kidney biopsy proven focal crescentic glomerulonephritis were also present in this patient. Anti-neutrophil cytoplasmic autoantibodies with specificity for proteinase 3 were detected in high titre during the active phase of the disease. This overlap syndrome with features indicating both Takayasu's arteritis and Wegener's granulomatosis suggests a common pathogenesis for these diseases.