Anti-neutrophil cytoplasmic antibodies (ANCA) : a seromarker for Wegener's granulomatosis
Turner, A.
Journal of Otolaryngology 20(4): 274-275
1991
ISSN/ISBN: 0381-6605 PMID: 1920582 Document Number: 375092
Wegener's granulomatosis can be a difficult diagnosis to establish. It is not uncommon to require repeated biopsies over many months for histologic confirmation. A recently developed seromarker--anti-neutrophil cytoplasm antibody--ANCA (synonymous with anticytoplasmic autoantibody--ACPA) adds a new and valuable tool for diagnosis. The literature shows this to be a highly specific and sensitive test for Wegener's granulomatosis.
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