Electroneurographic and electromyographic assessment of rat skeletal muscle reinnervation after microsurgical implantation of nerve into muscle venter
Monach, J.; Drozdowski, W.; Skowroński, J.
Neurologia i Neurochirurgia Polska 28(1): 13-25
1994
ISSN/ISBN: 0028-3843 PMID: 8028700 Document Number: 429649
The purpose of the study was an assessment of the reinnervation of paralysed rat muscles after implantation of nerve into muscle venter (neurotization). The study was carried out in three groups of rats, with neurotization performed in two groups, the third group served as control. Reinnervation was assessed by means of electroneurography (eng) and electromyography (emg) during electrostimulation of the implanted nerve. Latency and amplitude of M response were evaluated quantitatively. The study demonstrated that functional reinnervation of muscle after nerve implantation into its venter was possible, and the process of reinnervation developed at the highest rate within 16 weeks after neurotization. The use of nerve graft bridging the distance between the stump of the severed nerve and the denervated muscle had no unfavourable effect on the end-result of neurotization.