Galactorrhea-amenorrhea: psychological interaction with neuroendocrine function

Zacur, H.A.; Chapanis, N.P.; Lake, C.R.; Ziegler, M.; Tyson, J.E.; Zacur, H.A; Chapanis, N.P; Lake, C.R; Ziegler, M; Tyson, J.E

doi:10.1016/0002-9378(76)90863-2

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Galactorrhea-amenorrhea: psychological interaction with neuroendocrine function

Zacur, H.A.; Chapanis, N.P.; Lake, C.R.; Ziegler, M.; Tyson, J.E.

American Journal of Obstetrics and Gynecology 125(6): 859-862

1976

ISSN/ISBN: 0002-9378

PMID: 779478

DOI: 10.1016/0002-9378(76)90863-2

Document Number: 429378

Further substantiation of the interaction between psychological disease and the onset of galactorrhea-amenorrhea is presented in women who underwent intensive psychometric and neuroendocrine evaluation prior to the use of the dopamine against 2-Br-alpha-ergocryptine (CB-154). Normalization of a previously distorted psychometric test profile in each woman was accompanied by a profound decline in prolactin and an unexpected alteration in the peripheral concentrations of norepinephrine and dopamine-beta-hydroxylase. Cesation of galactorrhea and resumption of menses were observed in each instance.