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Dermal toxicity of hexachlorocyclohexane and pirimiphos-methyl in female rats

Raizada, R.B.; Srivastava, M.K.; Kaushal, R.A.; Singh, R.P.; Gupta, K.P.; Dikshith, T.S.

Veterinary and Human Toxicology 36(2): 128-130

1994

ISSN/ISBN: 0145-6296
PMID: 7515208
Document Number: 428916
Technical hexachlorocyclohexane (100 mg/kg/d) and pirimiphosmethyl EC 50 (250 mg/kg/d) given individually and in combination to female rats for 7, 15 or 30 d by skin application caused poisoning, pathomorphological changes in vital organs, and significant enzymatic changes in liver and serum. The changes produced by the 2 compounds in combination did not suggest potentiation at the tested dose levels.

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