Tuberous sclerosis complex: a review with a study of eight cases
Malik, A.S.; Hussin, Z.A.; Shriwas, S.R.; Kasim, Z.M.
Medical Journal of Malaysia 49(4): 375-384
1994
ISSN/ISBN: 0300-5283 PMID: 7674974 Document Number: 428263
This paper reviews the subject of tuberous sclerosis complex and presents data in eight cases of this condition, admitted to Hospital Universiti Sains Malaysia over a period of 8.5 years. The average age at presentation was 53 months. Seizures were the most common presenting feature. Male to female ratio was 3:1. Family history was present in four patients. All of the patients had one or more skin lesions. Six of them had retinal in six patients. Two patients had renal angiomyolipomas. A high index of hamartomas. Cardiac tumours were found in two patients. Multiple subependymal hamartomas were detected in six patients. Two patients had renal angiomyolipomas. A high index of suspicion and a detailed physical examination is required to diagnose this rare disorder.