Statistic evaluation of prognostic risk factors in penetrating keratoplasty using Cox multiple regression model
Yamagami, S.; Suzuki, Y.; Ohya, T.; Murao, M.; Miyata, K.; Tsuru, T.
Nippon Ganka Gakkai Zasshi 98(8): 777-781
1994
ISSN/ISBN: 0029-0203 PMID: 7942340 Document Number: 427589
Preoperative risk factors that may influence the prognosis in penetrating keratoplasty were statistically analyzed on 698 consecutive eye that had been operated on at the University of Tokyo Hospital. A Cox multiple regression model (proportional hazards models) was constructed with simultaneous consideration of follow-up periods and prognostic factors. Six preoperative risk factors were identified: corneal endothelial damage, the presence of anterior synechiae, glaucoma, older donor age, the area of vascularization, and aphakia or pseudophakia. Simulations of the prognosis were attempted using the significant factors.