Detection of cervical human papillomavirus infection from women with external genital condyloma acuminata
Song, X.H.; Yu, X.M.; Weng, L.J.
Zhonghua Fu Chan Ke Za Zhi 29(11): 673
1994
ISSN/ISBN: 0529-567X PMID: 7712891 Document Number: 425597
Cervical biopsy specimens were taken from 36 women with external genital condyloma acuminata in order to diagnose a concomitant cervical human papillomavirus (HPV) infection. Positive HPV infection rate of cervix was 16% (6/36) by routine visual examination, 69% (25/36) by colposcopy and 56% (18/32) by pathology. Among those patients 31% (10/32) have grade I-II cervical intraepithelial neoplasia (CIN) according to pathology. In 8 cases, both vulva and cervical specimens were examined by Southern blot, dot blot and polymerase chain reaction (PCR) technique. HPV DNA positive was detected in 7 of 8 cervical specimens. It is concluded cervical HPV infection was rather common in women with external genital condyloma acuminata and it is valuable to examine cervical HPV infection by colposcopy and biopsy to detect the concomitant CIN.