Analytical and chemical profile of pidotimod
Crimella, T.; Orlandi, R.; Bocchiola, G.; Anders, U.; Stradi, R.
Arzneimittel-Forschung 44(12a): 1405-1410
1994
ISSN/ISBN: 0004-4172 PMID: 7857332 Document Number: 424658
Pidotimod ((R)-3-[(S)-(5-oxo-2-pyrrolidinyl)carbonyl]-thiazolidine- 4-carboxylic acid, PGT/1A, CAS 121808-62-6) is a new synthetic immunostimulant, which has proved to possess a high activity. This paper describes its physico-chemical properties, structural identification including polymorphism, detection of impurities, determination of related compounds, separation, quantification and purity assay using high-performance liquid chromatography (HPLC).