Susceptibility of multiresistant serotype 012 Pseudomonas aeruginosa to fosfomycin in combination with other antibiotics
Watine, J.; Bourrel, C.; Dubourdieu, B.; Gineston, J.L.; Bories, P.; Durand, M.; Marre, A.; Formosa, F.; Brunel, M.P.; Palliez, J.
Pathologie-Biologie 42(4): 293-295
1994
ISSN/ISBN: 0369-8114 PMID: 7808781 Document Number: 423831
Serotype 012 represented 15% of 244 isolates of Pseudomonas aeruginosa isolated in the hospital over a 2 year period and most isolates of this serotype were resistant to multiple antibiotics. Combination experiments showed that fosfomycin and amikacin together were active against 92% of 012 isolates. It is recommended that serotyping be used systematically to identify 012 strains rapidly and fosfomycin/amikacin be considered as a presumptive antipseudomonal therapy in 012 infections.