An unusual reaction to alpha interferon in a case of non Hodgkin's lymphoma
Miglino, M.; Pierri, I.; Canepa, L.; Carrara, P.; Celesti, L.; Gobbi, M.
Haematologica 78(6): 411-413
1993
ISSN/ISBN: 0390-6078 PMID: 8175038 Document Number: 421722
A 64-year-old man suffering from non Hodgkin's lymphoma in progression and resistant to conventional chemotherapy was treated with alpha interferon. In a few days he developed an unusual adverse reaction characterized by severe dermatological and neuromuscular toxicity. We describe the case and suggest a possible pathogenetic mechanism for this rare event.
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