Effect of gynecologic abdominal surgery on function of the hypophyseal-thyroid axis
Kniazewski, B.; Olejek, A.; Rzempołuch, J.
Polski Tygodnik Lekarski 48(27-28): 590-594
1993
ISSN/ISBN: 0032-3756 PMID: 8090648 Document Number: 421286
Triiodothyronine (T3), free triiodothyronine (fT3), thyroxine (T4), free thyroxine, and TSH levels have been assayed in female patients undergoing gynecological surgeries of various extension (Wertheim-Meigs operation, pan-hysterectomy, unilateral adnexectomy, diagnostic laparoscopy). Laparoscopy did not produce any significant changes in the concentrations of assayed hormones. The remaining operations produced a decrease in T3 and fT3 levels and significant increase in T4 and fT4. TSH concentration also increased but this process was biphasic--an early decrease to baseline values follow by an increase. The assay of hypophyseal and thyroid hormones may serve as an indicator of the degree of the homeostasis disorders after surgical operations.