The influence of oral contraceptive no. II on platelet function and blood coagulability
Ding, H.Y.
Sheng Zhi Yu Bi Yun 5(3): 25-27
1985
ISSN/ISBN: 0253-357X PMID: 12340682 Document Number: 420513
The influence of the No. II oral contraceptive on platelet function and blood coagulability were studied in 65 women who had taken the drug for 1 to 17 (average 6.7) years. 20 women who hadn't taken any contraceptive served as controls. Results showed that platelet aggregation, adhesive rates, and fibrinogen levels were significantly increased than in the control group (P0.001). Factor VIII related antigen was slightly elevated, but not statistically significant. Antithrombin activity was significantly decreased (P0.001). The possibility of acute myocardial infarction and thromboembolic diseases are discussed and measures for prevention suggested.