HLA and ragweed allergy
Blumenthal, M.; Mendell, N.R.; Yunis, E.; Amos, D.B.; Muscoplat, C.; Elston, R.C.
Monographs in Allergy 11: 83-88
1977
ISSN/ISBN: 0077-0760 PMID: 876131 Document Number: 4191
In summary, two large families were subjected to genetic analysis of the distribution of the immune response. S linkage analysis indicated that this locus for positive skin test reaction to antigen E and/or personal history or seasonal allergy is linked to HLA-B. The maximum likelihood estimate of the recombination frequency is 0.13 in males and 0.53 in females, with a lod score of 2.53.
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