Mechanisms of bone loss associated with total hip replacement
Jacobs, J.J.; Sumner, D.R.; Galante, J.O.
Orthopedic Clinics of North America 24(4): 583-590
1993
ISSN/ISBN: 0030-5898 PMID: 8414423 Document Number: 417331
The pathogenesis of bone loss after total hip arthroplasty is discussed. Two separate processes are considered: adaptive bone remodeling ("stress-shielding") and osteolysis. Clinical and experimental studies that provide the basis for current and future strategies to minimize the occurrence and severity of these phenomena are summarized.
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