Quantitative determination of the accessible surface of globular proteins by tritium planigraphy
Gedrovich, A.V.; Baratova, L.A.; Bogacheva, E.N.; Medvedkin, V.N.; Shishkov, A.V.
Molekuliarnaia Biologiia 27(2): 309-315
1993
ISSN/ISBN: 0026-8984 PMID: 8487762 Document Number: 416989
At the last time the term "accessible surface" is used for a description of protein structure. The tritium planigraphy was used for quantitative detection of the accessible surface. The experimental dependence of an interaction probability of the tritium atoms with globular proteins with calculated accessible surface areas was obtained. The method was proposed on the basis of the information about the reactivity of amino acids residues and was used for the determination of an accessible surface of parvalbumin III of pike.