Ultrastructural changes in atrial cardiomyocytes in endotoxic shock
Bardakhch'ian, E.A.; Kharlanova, N.G.
Kardiologiia 33(2): 46-50
1993
ISSN/ISBN: 0022-9040 PMID: 8084129 Document Number: 416374
The distribution of atrial cardiomyocytic granules was studied in the early and intermediate periods of endotoxin shock in experiments with rabbits and dogs. The earliest alterations were marked by stimulation of cell secretory activity. At the same time the capillaries showed signs of disturbed microcirculation and increased permeability. The changes in the atrial nerve apparatus were reversible. The structural abnormalities were evolving in the intermediate period of endotoxin shock. There was a correlation between the development of vacuolar dystrophy and the levels of glycogen. Some nerve fibers displayed degenerative changes.