Pregnancy after BMT: three case reports
Lipton, J.H.; Derzko, C.; Fyles, G.; Meharchand, J.; Messner, H.A.
Bone Marrow Transplantation 11(5): 415-418
1993
ISSN/ISBN: 0268-3369 PMID: 8504278 Document Number: 415952
A case of successful pregnancy after BMT in a 24-year-old woman with ALL, conditioned with CY, L-asparaginase, methylprednisolone and total body irradiation (TBI) is reported. A second case of two spontaneously aborted pregnancies in a woman transplanted for ALL at the age of 29 years using CY and TBI conditioning and a third case, this time a successful pregnancy in a woman transplanted for AML at age 27 years using CY and TBI conditioning are also described. There are now 6 successful live births after TBI reports of, versus 16 following regimens in which no TBI is used. This is the first report of a successful pregnancy reported in a female transplanted when older than 25 years using any TBI-containing regimen.