Growth rate analysis of pulmonary metastases in giant cell tumor of bone
Osaka, S.; Toriyama, M.; Sato, E.; Kawano, H.; Taira, K.; Ohata, M.; Irako, M.; Yamaguchi, T.; Saotome, K.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 20(10): 1381-1386
1993
ISSN/ISBN: 0385-0684 PMID: 8346937 Document Number: 415291
We reviewed six cases with pulmonary metastases in giant cell tumor of bone. The growth rate and the doubling time of pulmonary metastases was measured and compared to the clinical course. The six cases were classified into two each of the following three types: 1) spontaneous remission, 2) continuously slow growing and 3) rapid growing. A favorable factor was a doubling time of more than 80 days in pulmonary metastases. A poor prognosis was indicated by a doubling time of around 30 days. Aggressive primary lesions should be excised widely.