Failure of intravenous immunoglobulins in certain systemic diseases. 5 cases
Bahadoran, P.; De Bandt, M.; Echard, M.; Jarrousse, B.; Guillevin, L.
Presse Medicale 22(25): 1175-1178
1993
ISSN/ISBN: 0755-4982 PMID: 8105460 Document Number: 415249
Human polyvalent immunoglobulins administered intravenously have shown to be effective in some immune diseases. We administered high dose-IV Ig (2g/kg/session) in five patients with severe chronic systemic diseases. Their condition did not improve, except in one case where a transient response was noticed. Considering the inconsistent results and high cost of IV Ig, double blind studies are required to determine the conditions in which high dose IV Ig may be more effective than conventional treatments.