The use of intravenous immunoglobulins in the treatment of primary immunodeficiencies
Lewandowicz-Uszyńska, A.; Jankowski, A.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 30(180): 409-412
2011
ISSN/ISBN: 1426-9686 PMID: 21751549 Document Number: 653449
In this paper we present indications for use of intravenous immunoglobulins (IVIG). The role of IVIG in the therapy of immunodeficiency of IgG subclasses was underlined. The goal of the treatment is to obtain the immunoglobulin serum level sufficient to prevent patients against infections. The active component of IVIG is immunoglobulin G. The IVIG supplementation is required for agammaglobulinemia, common variable immunodeficiency diseases and some other serious immunodeficience. The probable side-effects of IVIG infusions are those associated with proteins transfusions, therefore the special caution during the infusion is required. However, the modern IVIG preparations are highly purified. The IVIG production techniques protect immunoglobulins against any unwanted changes and the procedures ensure patients against transmission of infections and unwanted reactions.