Behçet's disease: a review and a report of 12 cases from Sweden
Ek, L.; Hedfors, E.
Acta Dermato-Venereologica 73(4): 251-254
1993
ISSN/ISBN: 0001-5555 PMID: 7904097 Document Number: 414198
In a retrospective study of 12 patients with Behcet's disease, more than half were found to originate from the Near East, where the prevalence of the disease is known to be high. The immigrant patients were all males, whereas 3 of the 5 patients with Swedish ancestry were females. Certain differences emerged between the two groups, including different sex ratio and absence of HLA B5 association and pathergy skin reaction among the Swedish patients. Moreover, serious neurological and ocular symptoms showing no tendency to recede with age afflicted all the Swedish female patients. Urogenital symptoms were, besides ulcers, common in both groups, including prostatitis, uretritis, orchitis, chronic sterile cystitis and relapsing salpingitis. Although the material does not allow statistical inferences, the estimated prevalence was higher than expected among both Swedish and immigrant patients. Recent studies, including the diagnostic criteria proposed by the "International Study Group for Behcet's disease", are discussed in relation to previously used criteria as well as present findings. The sensitivity and specificity of the first mentioned criteria and the ones proposed by Mason and Barnes seemed equal.