Systematic study of the morphology of the immune and endocrine organs during the infectious process
Avtandilov, G.G.; Barsukov, V.S.
Arkhiv Patologii 55(1): 7-12
1993
ISSN/ISBN: 0004-1955 PMID: 7980047 Document Number: 413937
Immune and endocrine organs of 259 children and adults who had died of sepsis, local purulent-inflammatory affections were studied morphologically and morphometrically. It is established, that compensatory morphological changes in the lymphoid tissue and endocrine organs are integrated into a united system the structural basis of which are numerous inter- and intra-organ correlations. A systemic interaction between the lymphoid and endocrine organs at early age is pronounced much weaker than in the adults. A progressive destruction of this systemic interaction takes place in sepsis and results in an increase of informational entropy and the coefficient of the system disintegration. Inability of the body to fight bacteremia and to localize the infection is secondary to the system destruction this being due to high frequency of previous immuno-endocrinopathies.