Kinetic potentials of certain scavenger enzymes in fresh water snails susceptible and non-susceptible to Schistosoma infection
Nabih, I.; el Ansary, A.
Cellular and Molecular Biology 39(4): 449-454
1993
ISSN/ISBN: 0145-5680 PMID: 8329984 Document Number: 413641
The activities of catalase (H-2O-2 - oxidoreductase EC 1.11.1.6) - and glutathione reductase (EC 1.6.4.2) as two important scavenger enzymes, were measured in tissue homogenates of Biomphalaria alexandrina and Bulinus truncatus, the snail vectors of Schistosomiasis. A parallel study was done on Lymnea truncatula snails which are not susceptible to Schistosoma infection. The apparent Michaelis constant (K-m) for both anzymes were determined in tissue homogenates of the three studied species. The results obtained showed that both susceptible species have higher affinity to hydrogen peroxide (H-2O-2) and oxidized glutathione (GSSG) than the non-susceptible one.