Olfactory neuroblastoma: clinical and pathological aspects

Lund, V.J.; Milroy, C.

Rhinology 31(1): 1-6

1993


ISSN/ISBN: 0300-0729
PMID: 7686684
Document Number: 412671
Twenty cases of olfactory neuroblastoma were available for clinical and histopathological evaluation. The usefulness of immunohistochemistry in the diagnosis of this tumour was investigated and was best achieved using a panel of monoclonal and polyclonal antibodies, notably neuron-specific enolase, PGP 9.5, S-100 protein, synaptophysin and chromogranin A. This study confirmed that immunohistochemistry is a useful adjunct to cases where conventional histology is equivocal.

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