Myocardial energetics
Ford, L.E.
Advances in Experimental Medicine and Biology 346: 39-49
1993
ISSN/ISBN: 0065-2598 PMID: 8184779 Document Number: 410495
Inotropic alterations may alter contractile efficiency. Positive inotropic agents act mainly, if not exclusively, by increasing activation, which has very little effect on contractile efficiency. The metabolic effects of hypoxia may depress the contractile machinery directly. Acidosis is likely to decrease efficiency while an elevated phosphate, by itself, is likely to have little effect on efficiency.